CD45 Antibody (YA6664)
(Synonyms: B220 antibody; CD45 antibody; CD45 antigen antibody; Glycoprotein antibody; GP180 antibody; L CA antibody; L-CA antibody; LCA antibody; Leukocyte common antigen antibody; Leukocyte common antigen precursor antibody; B220 antibody; CD45 antibody; CD45 antigen antibody; Glycoprotein antibody; GP180 antibody; L CA antibody; L-CA antibody; LCA antibody; Leukocyte common antigen antibody; Leukocyte common antigen precursor antibody; loc antibody; Ly-5 antibody; LY5 antibody; Lyt-4 antibody; Protein tyrosine phosphatase receptor type C antibody; Protein tyrosine phosphatase receptor type c polypeptide antibody; Ptprc antibody; PTPRC_HUMAN antibody; Receptor type tyrosine protein phosphatase C antibody; Receptor-type tyrosine-protein phosphatase C antibody; T200 antibody; T200 glycoprotein antibody; T200 leukocyte common antigen antibody; )CD45 Antibody (YA6664) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD45.
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Host:
Mouse
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Isotype:
IgG
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Application:
IHC-P, FC
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Reactivity :
Mouse
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:1000 | 1:1000 |
Product Details
CD45 Antibody (YA6664) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD45.
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Host Mouse
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Clonality Recombinant,Monoclonal
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Species ReactivityMouse
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Calculated Molecular Weight Predicted band size: 145 kDa
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD45 (PTPRC/LCA) is a receptor-type protein tyrosine phosphatase common to all white blood cells and is the most classic pan-marker of immune cells. CD45 can be used to label hematopoietic cells, regulate TCR, BCR, and NK cell activation signals, and control immune cell development, differentiation, and function.
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Membrane raft; Synapse
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Expression
Tissue_specificity:Isomer 1: Detected in thymocytes. Isomer 2: Detected in thymocytes. Isomer 3: Detected in thymocytes. Isomer 4: Not detected in thymocytes. Isomer 5: Detected in thymocytes. Isomer 6: Not detected in thymocytes. Isomer 7: Detected in thymocytes. Isomer 8: Not detected in thymocytes. -
Isoforms & Post-Translational Modification
CD45 has 8 isomers: P08575-3: 147486 Da (predicted); P08575-4: 131130 Da (predicted); P08575-5: 142623 Da (predicted); P08575-6: 142898 Da (predicted); P08575-7: 140582 Da (predicted); P08575-8: 138034 Da (predicted); P08575-9: 135719 Da (predicted); P08575-10: 135993 Da (predicted).
Heavily N- and O-glycosylated -
Subunit
Binds GANAB and PRKCSH (By similarity). Interacts with SKAP1. Interacts with DPP4; the interaction is enhanced in an interleukin-12-dependent manner in activated lymphocytes
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SwissProt ID
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Synonyms
B220 antibody; CD45 antibody; CD45 antigen antibody; Glycoprotein antibody; GP180 antibody; L CA antibody; L-CA antibody; LCA antibody; Leukocyte common antigen antibody; Leukocyte common antigen precursor antibody; B220 antibody; CD45 antibody; CD45 antigen antibody; Glycoprotein antibody; GP180 antibody; L CA antibody; L-CA antibody; LCA antibody; Leukocyte common antigen antibody; Leukocyte common antigen precursor antibody; loc antibody; Ly-5 antibody; LY5 antibody; Lyt-4 antibody; Protein tyrosine phosphatase receptor type C antibody; Protein tyrosine phosphatase receptor type c polypeptide antibody; Ptprc antibody; PTPRC_HUMAN antibody; Receptor type tyrosine protein phosphatase C antibody; Receptor-type tyrosine-protein phosphatase C antibody; T200 antibody; T200 glycoprotein antibody; T200 leukocyte common antigen antibody;
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