Nr1i3 - nuclear receptor subfamily 1, group I, member 3 Gene

Also Known as CAR; MB67; Care2; ESTM32; CAR-beta

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12355

Summary

Enables DNA binding activity. Acts upstream of or within negative regulation of transcription, DNA-templated. Located in cytosol and nucleus. Is expressed in genitourinary system; heart; and hemolymphoid system. Orthologous to human NR1I3 (nuclear receptor subfamily 1 group I member 3). [provided by Alliance of Genome Resources, Apr 2022]

Nr1i3 Products (6)

mRNA Protein Name
NM_001243062.1 NP_001229991.1 nuclear receptor subfamily 1 group I member 3 isoform 2
NM_001243063.1 NP_001229992.1 nuclear receptor subfamily 1 group I member 3 isoform 3
NM_009803.5 NP_033933.2 nuclear receptor subfamily 1 group I member 3 isoform 1
NM_001243062.1 NP_001229991.1 nuclear receptor subfamily 1 group I member 3 isoform 2
NM_001243063.1 NP_001229992.1 nuclear receptor subfamily 1 group I member 3 isoform 3
NM_009803.5 NP_033933.2 nuclear receptor subfamily 1 group I member 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables DNA binding IDA
IDA: Inferred from direct assay
11891224 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11891224 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11891224 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11891224 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17904126 MGI
located in cytosol IDA
IDA: Inferred from direct assay
12885400 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12885400 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor subfamily 1 group I member 3

  • constitutive androstane receptor

  • constitutively transactivates RAREs

  • orphan nuclear receptor MB67

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS09535 NR1I3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20068 Nr1i3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26572 Nr1i3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr1i3 NCBI NCBI:9970