Il5ra - interleukin 5 receptor, alpha Gene

Also Known as Il5r; CD125; CDw125

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16192

Summary

Predicted to enable cytokine binding activity and cytokine receptor activity. Acts upstream of or within cellular response to organic substance; inflammatory response to antigenic stimulus; and regulation of interleukin-5 production. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in early conceptus. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL5RA (interleukin 5 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il5ra Products (1)

mRNA Protein Name
NM_008370.2 NP_032396.1 interleukin-5 receptor subunit alpha precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
10848907 MGI
acts upstream of or within regulation of interleukin-5 production IMP
IMP: Inferred from mutant phenotype
10848907 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-5 receptor subunit alpha

  • IL-5 receptor alpha chain

  • IL-5 receptor subunit alpha

  • IL-5R subunit alpha

Recombinant Il5ra Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P72540 IL-5R alpha Protein, Mouse (HEK293, His) P21183 (D18-H339) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75864 IL-5R alpha Protein, Mouse (sf9, His) P21183 (M1-V328) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS06773 IL5RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174601 Human IL5RA mRNA / Unkown
HY-RS19696 Il5ra Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26191 Il5ra Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P9923A Benralizumab (anti-IL5RA ) Inducer 99.60% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il5ra NCBI NCBI:3568