Mboat7 - membrane bound O-acyltransferase domain containing 7 Gene

Also Known as BB1; Leng4; Lpiat; Lpiat1; LPLAT 7; m-mboa-7; 5730589L02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77582

Summary

Enables O-acyltransferase activity and lysophospholipid Acyltransferase activity. Involved in phosphatidylinositol acyl-chain remodeling and regulation of triglyceride metabolic process. Acts upstream of or within layer formation in cerebral cortex; phosphatidylinositol metabolic process; and ventricular system development. Located in membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Used to study hydrocephalus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human MBOAT7 (membrane bound O-acyltransferase domain containing 7). [provided by Alliance of Genome Resources, Apr 2022]

Mboat7 Products (1)

mRNA Protein Name
NM_029934.4 NP_084210.2 lysophospholipid acyltransferase 7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables O-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
23472195 MGI
enables lysophospholipid acyltransferase activity IMP
IMP: Inferred from mutant phenotype
23097495 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within layer formation in cerebral cortex IMP
IMP: Inferred from mutant phenotype
23097495 MGI
involved in phosphatidylinositol acyl-chain remodeling IMP
IMP: Inferred from mutant phenotype
32253259 MGI
acts upstream of or within phosphatidylinositol metabolic process IMP
IMP: Inferred from mutant phenotype
23472195 MGI
involved in regulation of triglyceride metabolic process IMP
IMP: Inferred from mutant phenotype
32253259 MGI
acts upstream of or within ventricular system development IMP
IMP: Inferred from mutant phenotype
21746835 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in membrane IDA
IDA: Inferred from direct assay
23097495 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysophospholipid acyltransferase 7

  • 1-acylglycerophosphatidylinositol O-acyltransferase

  • bladder and breast carcinoma-overexpressed gene 1 protein

  • leukocyte receptor cluster (LRC) member 4

  • lysophosphatidylinositol acyltransferase 1

  • membrane-bound O-acyltransferase domain-containing prote

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08195 MBOAT7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mboat7 NCBI NCBI:79143