Acetylserotonin O-methyltransferase

Definition:

[Isoform 1]: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine).; [Isoform 2]: Does not show Acetylserotonin O-methyltransferase activity.; [Isoform 3]: Does not show Acetylserotonin O-methyltransferase activity.

References:

[1]. Hany Goubran Botros, et al. Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway. J Pineal Res. 2013 Jan;54(1):46-57. [Content Brief]

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