Acquired idiopathic generalized anhidrosis

Definition

Acquired idiopathic generalized anhidrosis (AIGA) is a rare condition, characterized by generalized absence of sweating without other autonomic and neurologic dysfunction. Most of the cases reported are Japanese. Various pathomechanisms proposed were idiopathic sudomotor dysfunction, sudomotor neuropathy, sweat gland abnormalities and occlusion of proximal duct. The etiology of AIGA remains unclear because of the rarity of this syndrome. According to the limited studies available, various pathologic abnormalities have been reported. Many patients have associated cholinergic urticaria and raised IgE levels. Immunologic mechanisms are considered to be contributory to the disease. Treatment of AIGA almost always comprises steroid pulse therapy or high-dose oral steroids.

References:

[1]. Geethu Gangadharan, et al. Acquired Idiopathic Generalized Anhidrosis. Indian J Dermatol. 2015 Jul-Aug;60(4):422. [Content Brief]

[2]. Y Ohshima, et al. Treatment of patients with acquired idiopathic generalized anhidrosis. Br J Dermatol. 2013 Feb;168(2):430-2. [Content Brief]

[3]. Yin-Chun Chen, et al. Identification of subgroups of acquired idiopathic generalized anhidrosis. Neurologist. 2008 Sep;14(5):318-20. [Content Brief]

生物医学辞典

生物医学辞典は、生物学の学術用語と専門データの包括的で専門的なデータベースです。すべての説明は、権威ある書籍や高いＩＦの文献に基づいており、知りたい生物医学用語の正確な説明を得ることができます。

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