AP2-associated protein kinase 1
Definition:
References:
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[1]. Sean D Conner, et al. AAK1-mediated micro2 phosphorylation is stimulated by assembled clathrin. Traffic. 2003 Dec;4(12):885-90. [Content Brief]
[2]. Sean D Conner, et al. Differential requirements for AP-2 in clathrin-mediated endocytosis. J Cell Biol. 2003 Sep 1;162(5):773-9. [Content Brief]
[3]. Erika B Sorensen, et al. AAK1 regulates Numb function at an early step in clathrin-mediated endocytosis. Traffic. 2008 Sep;9(10):1791-800. [Content Brief]
[4]. Davin M Henderson, et al. A novel AAK1 splice variant functions at multiple steps of the endocytic pathway. Mol Biol Cell. 2007 Jul;18(7):2698-706. [Content Brief]
[5]. Neetu Gupta-Rossi, et al. The adaptor-associated kinase 1, AAK1, is a positive regulator of the Notch pathway. J Biol Chem. 2011 May 27;286(21):18720-30. [Content Brief]
[6]. Sean D Conner, et al. Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis. J Cell Biol. 2002 Mar 4;156(5):921-9. [Content Brief]
[7]. Doris Ricotta, et al. Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals. J Cell Biol. 2002 Mar 4;156(5):791-5. [Content Brief]
[8]. Gregory Neveu, et al. AP-2-associated protein kinase 1 and cyclin G-associated kinase regulate hepatitis C virus entry and are potential drug targets. J Virol. 2015 Apr;89(8):4387-404. [Content Brief]
[9]. Sven Verdonck, et al. Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity. J Med Chem. 2019 Jun 27;62(12):5810-5831. [Content Brief]