BolA-like protein 2

Definition:

Acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts together with the monothiol glutaredoxin GLRX3.

References:

[1]. Lucia Banci, et al. Elucidating the Molecular Function of Human BOLA2 in GRX3-Dependent Anamorsin Maturation Pathway. J Am Chem Soc. 2015 Dec 30;137(51):16133-43. [Content Brief]

[2]. Avery G Frey, et al. A Glutaredoxin·BolA Complex Serves as an Iron-Sulfur Cluster Chaperone for the Cytosolic Cluster Assembly Machinery. J Biol Chem. 2016 Oct 21;291(43):22344-22356. [Content Brief]

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