C-C chemokine receptor type 3

Definition:

Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1.; (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.

References:

[1]. A Albini, et al. HIV-1 Tat protein mimicry of chemokines. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13153-8. [Content Brief]

[2]. C Combadiere, et al. Cloning and functional expression of a human eosinophil CC chemokine receptor. J Biol Chem. 1995 Jul 14;270(28):16491-4. [Content Brief]

[3]. B L Daugherty, et al. Cloning, expression, and characterization of the human eosinophil eotaxin receptor. J Exp Med. 1996 May 1;183(5):2349-54. [Content Brief]

[4]. P D Ponath, et al. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med. 1996 Jun 1;183(6):2437-48. [Content Brief]

[5]. Joon Sung Park, et al. Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity. Int J Biol Macromol. 2018 Dec;120(Pt A):835-845. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.