cAMP-dependent protein kinase A (PKA)

Definition:

cAMP-dependent protein kinase A (PKA) is an enzyme that modulates Hh signaling activity through phosphorylating the transcription factor Cubitus interruptus (Ci) and G protein coupled receptor (GPCR) family protein Smoothened (Smo).

References:

[1]. Chen P, et al. Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A. Sci Rep. 2017 Jun 6;7(1):2891. [Content Brief]

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