Ceramide synthase 2

[1]. Hyun Joon Kim, et al. A fluorescent assay for ceramide synthase activity. J Lipid Res. 2012 Aug;53(8):1701-7. [Content Brief]

[2]. Rotem Tidhar, et al. Eleven residues determine the acyl chain specificity of ceramide synthases. J Biol Chem. 2018 Jun 22;293(25):9912-9921. [Content Brief]

[3]. Yusuke Ohno, et al. ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18439-44. [Content Brief]

[4]. Sujoy Lahiri, et al. Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine. FEBS Lett. 2007 Nov 13;581(27):5289-94. [Content Brief]

[5]. Takayuki Sassa, et al. Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region. J Biol Chem. 2016 Apr 1;291(14):7477-87. [Content Brief]

[6]. Yukiko Mizutani, et al. 2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length. J Lipid Res. 2008 Nov;49(11):2356-64. [Content Brief]

[7]. Stefka D Spassieva, et al. Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response. Biochem J. 2009 Nov 11;424(2):273-83. [Content Brief]

[8]. Rotem Tidhar, et al. Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain. J Biol Chem. 2012 Jan 27;287(5):3197-206. [Content Brief]

[9]. Elad L Laviad, et al. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J Biol Chem. 2008 Feb 29;283(9):5677-84. [Content Brief]