Chromodomain-helicase-DNA-binding protein 9

Definition:

Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis (By similarity).

References:

[1]. I Shur, et al. Characterization and functional analysis of CReMM, a novel chromodomain helicase DNA-binding protein. J Mol Biol. 2005 Sep 23;352(3):646-55. [Content Brief]

[2]. Sailesh Surapureddi, et al. PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex. Biochem Biophys Res Commun. 2006 May 5;343(2):535-43. [Content Brief]

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