Coiled-coil domain-containing protein 102B

Definition:

During interphase, forms fibers at the proximal ends of centrioles to maintain centrosome cohesion. During mitosis, dissociates from the centrosome following phosphorylation to allow centrosome separation. Contributes to CROCC/rootletin filament formation.

References:

[1]. Yuqing Xia, et al. CCDC102B functions in centrosome linker assembly and centrosome cohesion. J Cell Sci. 2018 Dec 3;131(23):jcs222901. [Content Brief]

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