Colonic spirochetosis

Definition:

Colonic spirochetosis (CS) is a disease caused by the Brachyspira genus, Brachyspira aalborgi and Brachyspira pilosicoli. B. pilosicoli induces disease in both humans and animals, whereas B. aalborgi affects only humans and higher primates. CS is a polymicrobial disease characterized by persistent intimate mucosal epithelial cell attachment of spirochetes alone or together with certain enterohepatic Helicobacter species. Symptoms in humans include diarrhea, rectal bleeding, and abdominal cramps.

References:

[1]. Changyou Lin, et al. Complete Genome Sequence of the Porcine Strain Brachyspira pilosicoli P43/6/78(T.). Genome Announc. 2013 Jan;1(1):e00215-12. [Content Brief]

[2]. James L Smith, et al. Colonic spirochetosis in animals and humans. J Food Prot. 2005 Jul;68(7):1525-34. [Content Brief]

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