Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

Definition:

As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP.

References:

[1]. Kota N Gopalakrishna, et al. Mechanisms of mutant PDE6 proteins underlying retinal diseases. Cell Signal. 2017 Sep;37:74-80. [Content Brief]

[2]. Tanja Grau, et al. Decreased catalytic activity and altered activation properties of PDE6C mutants associated with autosomal recessive achromatopsia. Hum Mol Genet. 2011 Feb 15;20(4):719-30. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.