Cyclin-dependent kinase inhibitor 1B
Definition:
References:
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[1]. Arpita Ray, et al. p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes. Mol Cell Biol. 2009 Feb;29(4):986-99. [Content Brief]
[2]. Denise A McGrath, et al. Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins. EMBO J. 2017 Aug 1;36(15):2251-2262. [Content Brief]
[3]. Matthias Grimmler, et al. Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. Cell. 2007 Jan 26;128(2):269-80. [Content Brief]
[4]. N Ishida, et al. Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability. J Biol Chem. 2000 Aug 18;275(33):25146-54. [Content Brief]
[5]. Incheol Shin, et al. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med. 2002 Oct;8(10):1145-52. [Content Brief]
[6]. Laurence Bockstaele, et al. Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". Mol Cell Biol. 2006 Jul;26(13):5070-85. [Content Brief]
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