Cysteine proteases (CPs)

Definition:

Cysteine proteases (CPs) are proteins with molecular mass about 21–30 kDa. CPs play key roles in the pathogenesis of protozoan parasites, including cell/tissue penetration, hydrolysis of host or parasite proteins, autophagy, and evasion or modulation of the host immune response.

References:

[1]. Z Grzonka, et al. Structural studies of cysteine proteases and their inhibitors. Acta Biochim Pol. 2001;48(1):1-20. [Content Brief]

[2]. Jair L Siqueira-Neto, et al. Cysteine proteases in protozoan parasites. PLoS Negl Trop Dis. 2018 Aug 23;12(8):e0006512 [Content Brief]

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