Cytochrome P450 26A1
Definition:
References:
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[1]. Ariel R Topletz, et al. Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases. Biochem Pharmacol. 2012 Jan 1;83(1):149-63. [Content Brief]
[2]. J A White, et al. cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450. J Biol Chem. 1997 Jul 25;272(30):18538-41. [Content Brief]
[3]. Robert S Foti, et al. Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1. J Pharmacol Exp Ther. 2016 May;357(2):281-92. [Content Brief]
[4]. E Sonneveld, et al. Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells. Cell Growth Differ. 1998 Aug;9(8):629-37. [Content Brief]
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