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Electron transfer flavoprotein beta subunit lysine methyltransferase

Definition:

Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain.

References:

[1]. Virginie F Rhein, et al. Human METTL20 methylates lysine residues adjacent to the recognition loop of the electron transfer flavoprotein in mitochondria. J Biol Chem. 2014 Aug 29;289(35):24640-51. [Content Brief]

[2]. Jędrzej Małecki, et al. Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity. J Biol Chem. 2015 Jan 2;290(1):423-34. [Content Brief]

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