GLP-1 receptor (GLP-1R)

Definition:

GLP-1 receptor (GLP-1R) is a receptor protein expressed on beta cells of the pancreas and neurons of the brain. GLP-1R interacts with GLP-1 and plays a key role in reducing neuroinflammation, promoting nerve growth, improving heart function, suppressing appetite, delaying gastric emptying, regulating blood lipid metabolism and reducing fat deposition.

References:

[1]. Zhao X, et al. GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects. Front Endocrinol (Lausanne). 2021 Aug 23;12:721135. [Content Brief]

Biomedical Dictionary

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