Glutamate receptor ionotropic, NMDA 2D
Definition:
References:
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[1]. S D Hess, et al. Functional characterization of human N-methyl-D-aspartate subtype 1A/2D receptors. J Neurochem. 1998 Mar;70(3):1269-79. [Content Brief]
[2]. David H Hackos, et al. Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron. 2016 Mar 2;89(5):983-99. [Content Brief]
[3]. Kevin K Ogden, et al. Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology. PLoS Genet. 2017 Jan 17;13(1):e1006536. [Content Brief]
[4]. Dong Li, et al. GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers. Am J Hum Genet. 2016 Oct 6;99(4):802-816. [Content Brief]
[5]. Wenjuan Chen, et al. Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy. Mol Pharmacol. 2017 Apr;91(4):317-330. [Content Brief]
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