Glycoprotein hormones alpha chain
Definition:
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
References:
-
[1]. Xuliang Jiang, et al. Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer. J Biol Chem. 2014 May 16;289(20):14273-82. [Content Brief]
[2]. J L Keene, et al. Expression of biologically active human follitropin in Chinese hamster ovary cells. J Biol Chem. 1989 Mar 25;264(9):4769-75. [Content Brief]
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
