Hereditary elliptocytosis

Definition:

Hereditary elliptocytosis (EL) is an autosomal dominant hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia caused by fragility of the erythrocyte membrane skeleton due to defects in alpha-spectrin, beta-spectrin, or protein 4.1.

References:

[1]. Jean Delaunay, et al. The molecular basis of hereditary red cell membrane disorders. Blood Rev. 2007 Jan;21(1):1-20. [Content Brief]

[2]. Patrick G Gallagher, et al. Hereditary elliptocytosis: spectrin and protein 4.1R. Semin Hematol. 2004 Apr;41(2):142-64. [Content Brief]

[3]. Xiuli An, et al. Disorders of red cell membrane. Br J Haematol. 2008 May;141(3):367-75. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.