Insulinoma-associated protein 1
Definition:
References:
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[1]. Georg Mellitzer, et al. IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas. EMBO J. 2006 Mar 22;25(6):1344-52. [Content Brief]
[2]. Tao Zhang, et al. Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest. J Biol Chem. 2009 Feb 27;284(9):5574-81. [Content Brief]
[3]. Hong-Wei Wang, et al. Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription. J Endocrinol. 2008 Jul;198(1):29-39. [Content Brief]
[4]. Marcello Tortorici, et al. Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase. ACS Chem Biol. 2013 Aug 16;8(8):1677-82. [Content Brief]
[5]. Wei-Dong Liu, et al. INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases. Biochem J. 2006 Jul 1;397(1):169-77. [Content Brief]
[6]. Mary B Breslin, et al. Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence. Nucleic Acids Res. 2002 Feb 15;30(4):1038-45. [Content Brief]