Ion exchange chromatography (IEC)

Definition:

Ion exchange chromatography (IEC)1 is a widely used separation technique for protein purification. IEC is useful for fractionation of crude lysates during the early stages of protein purification as well as for removing trace contaminants during final polishing steps.

References:

[1]. Robert S Chumanov, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9. [Content Brief]

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