Ly6/PLAUR domain-containing protein 3

Definition:

Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.

References:

[1]. J Würfel, et al. Cloning of the human homologue of the metastasis-associated rat C4.4A. Gene. 2001 Jan 10;262(1-2):35-41. [Content Brief]

[2]. Line V Hansen, et al. Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor. Biochem J. 2004 Jun 15;380(Pt 3):845-57. [Content Brief]

[3]. B A Smith, et al. Identification of genes involved in human urothelial cell-matrix interactions: implications for the progression pathways of malignant urothelium. Cancer Res. 2001 Feb 15;61(4):1678-85. [Content Brief]

[4]. G C Fletcher, et al. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. Br J Cancer. 2003 Feb 24;88(4):579-85. [Content Brief]

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