Methylcytosine dioxygenase TET2
Definition:
References:
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[1]. Qiang Chen, et al. TET2 promotes histone O-GlcNAcylation during gene transcription. Nature. 2013 Jan 24;493(7433):561-4. [Content Brief]
[2]. Lulu Hu, et al. Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation. Cell. 2013 Dec 19;155(7):1545-55. [Content Brief]
[3]. Saskia M C Langemeijer, et al. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat Genet. 2009 Jul;41(7):838-42. [Content Brief]
[4]. Myunggon Ko, et al. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature. 2010 Dec 9;468(7325):839-43. [Content Brief]
[5]. Rachel Deplus, et al. TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J. 2013 Mar 6;32(5):645-55. [Content Brief]
[6]. Yu-Fei He, et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science. 2011 Sep 2;333(6047):1303-7. [Content Brief]
[7]. Jarmila Stremenova Spegarova, et al. Germline TET2 loss of function causes childhood immunodeficiency and lymphoma. Blood. 2020 Aug 27;136(9):1055-1066. [Content Brief]
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