Mitochondrial import inner membrane translocase subunit TIM50

Definition:

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

References:

[1]. Yin Guo, et al. Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death. J Biol Chem. 2004 Jun 4;279(23):24813-25. [Content Brief]

[2]. Hongzhi Xu, et al. Tim50a, a nuclear isoform of the mitochondrial Tim50, interacts with proteins involved in snRNP biogenesis. BMC Cell Biol. 2005 Jul 11;6(1):29. [Content Brief]

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