myeloperoxidase (MPO)

Definition:

Myeloperoxidase (MPO) is a heme-containing peroxidase expressed mainly in neutrophils and to a lesser degree in monocytes.Myeloperoxidase (MPO)catalyzes the formation of reactive oxygen intermediates hypochlorous acid (HOCl). The MPO/HOCl system plays an important role in microbial killing by neutrophils.

References:

[1]. Aratani Y. Myeloperoxidase: Its role for host defense, inflammation, and neutrophil function. Arch Biochem Biophys. 2018 Feb 15;640:47-52. [Content Brief]

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