N-acetylglutamate synthase, mitochondrial

Definition:

Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity.

References:

[1]. C Bachmann, et al. Purification and properties of acetyl-CoA:L-glutamate N-acetyltransferase from human liver. Biochem J. 1982 Jul 1;205(1):123-7. [Content Brief]

[2]. Ljubica Caldovic, et al. Cloning and expression of the human N-acetylglutamate synthase gene. Biochem Biophys Res Commun. 2002 Dec 13;299(4):581-6. [Content Brief]

[3]. Gengxiang Zhao, et al. Crystal structure of the N-acetyltransferase domain of human N-acetyl-L-glutamate synthase in complex with N-acetyl-L-glutamate provides insights into its catalytic and regulatory mechanisms. PLoS One. 2013 Jul 24;8(7):e70369. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.