Neutrophil cytosol factor 2

Definition:

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).

References:

[1]. L Yoshida, et al. Expression of a p67(phox) homolog in Caco-2 cells giving O(2)(-)-reconstituting ability to cytochrome b(558) together with recombinant p47(phox). Biochem Biophys Res Commun. 2002 Sep 6;296(5):1322-8. [Content Brief]

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