Neutrophil defensin 1
Definition:
References:
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[1]. Gang Wei, et al. Trp-26 imparts functional versatility to human alpha-defensin HNP1. J Biol Chem. 2010 May 21;285(21):16275-85. [Content Brief]
[2]. Jason G Smith, et al. Mechanism of adenovirus neutralization by Human alpha-defensins. Cell Host Microbe. 2008 Jan 17;3(1):11-9. [Content Brief]
[3]. Bryan Ericksen, et al. Antibacterial activity and specificity of the six human {alpha}-defensins. Antimicrob Agents Chemother. 2005 Jan;49(1):269-75. [Content Brief]
[4]. Ehsan Hazrati, et al. Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection. J Immunol. 2006 Dec 15;177(12):8658-66. [Content Brief]
[5]. Erik de Leeuw, et al. Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II. FEBS Lett. 2010 Apr 16;584(8):1543-8. [Content Brief]
[6]. Guozhang Zou, et al. Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs. J Biol Chem. 2007 Jul 6;282(27):19653-65. [Content Brief]
[7]. Fang Wang, et al. Alarmin human α defensin HNP1 activates plasmacytoid dendritic cells by triggering NF-κB and IRF1 signaling pathways. Cytokine. 2016 Jul;83:53-60. [Content Brief]
[8]. Karsten Eichholz, et al. Adenovirus-α-Defensin Complexes Induce NLRP3-Associated Maturation of Human Phagocytes via Toll-Like Receptor 4 Engagement. J Virol. 2022 Mar 23;96(6):e0185021. [Content Brief]
[9]. Le Zhao, et al. Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 function. PLoS One. 2013 Nov 13;8(11):e78937. [Content Brief]
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