Novel acetylcholine receptor chaperone
Definition:
References:
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[1]. Shenyan Gu, et al. Brain α7 Nicotinic Acetylcholine Receptor Assembly Requires NACHO. Neuron. 2016 Mar 2;89(5):948-55. [Content Brief]
[2]. Jose A Matta, et al. NACHO Mediates Nicotinic Acetylcholine Receptor Function throughout the Brain. Cell Rep. 2017 Apr 25;19(4):688-696. [Content Brief]
[3]. Hae-Jin Kweon, et al. NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly. Cell Rep. 2020 Aug 11;32(6):108025. [Content Brief]
[4]. Elizabeth B Rex, et al. A Genome-Wide Arrayed cDNA Screen to Identify Functional Modulators of α7 Nicotinic Acetylcholine Receptors. SLAS Discov. 2017 Feb;22(2):155-165. [Content Brief]
[5]. Anish Deshpande, et al. Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of α7 Nicotinic Receptors in Mouse Brain?. Biomolecules. 2020 Mar 19;10(3):470. [Content Brief]
[6]. Simone Mazzaferro, et al. NACHO and 14-3-3 promote expression of distinct subunit stoichiometries of the α4β2 acetylcholine receptor. Cell Mol Life Sci. 2021 Feb;78(4):1565-1575. [Content Brief]