Poor drug metabolism

[1]. A Kaneko, et al. High frequencies of CYP2C19 mutations and poor metabolism of proguanil in Vanuatu. Lancet. 1997 Mar 29;349(9056):921-2. [Content Brief]

[2]. Elena A Gaikovitch, et al. Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population. Eur J Clin Pharmacol. 2003 Aug;59(4):303-12. [Content Brief]

[3]. Takaharu Mizutani, et al. PM frequencies of major CYPs in Asians and Caucasians. Drug Metab Rev. 2003 May-Aug;35(2-3):99-106. [Content Brief]