Rac GTPase-activating protein 1
Definition:
References:
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[1]. Jae-Seon Lee, et al. MgcRacGAP regulates cortical activity through RhoA during cytokinesis. Exp Cell Res. 2004 Feb 15;293(2):275-82. [Content Brief]
[2]. Keiju Kamijo, et al. Dissecting the role of Rho-mediated signaling in contractile ring formation. Mol Biol Cell. 2006 Jan;17(1):43-55. [Content Brief]
[3]. Ozlem Yüce, et al. An ECT2-centralspindlin complex regulates the localization and function of RhoA. J Cell Biol. 2005 Aug 15;170(4):571-82. [Content Brief]
[4]. T Kawashima, et al. MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells. Blood. 2000 Sep 15;96(6):2116-24. [Content Brief]
[5]. Fabian Oceguera-Yanez, et al. Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis. J Cell Biol. 2005 Jan 17;168(2):221-32. [Content Brief]
[6]. Sergey Lekomtsev, et al. Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis. Nature. 2012 Dec 13;492(7428):276-9. [Content Brief]
[7]. K Hirose, et al. MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody. J Biol Chem. 2001 Feb 23;276(8):5821-8. [Content Brief]
[8]. Wei-meng Zhao, et al. MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13158-63. [Content Brief]
[9]. Benjamin A Wolfe, et al. Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. PLoS Biol. 2009 May 5;7(5):e1000110. [Content Brief]
[10]. Masanori Mishima, et al. Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. Dev Cell. 2002 Jan;2(1):41-54. [Content Brief]
[11]. Sandeep N Wontakal, et al. RACGAP1 variants in a sporadic case of CDA III implicate the dysfunction of centralspindlin as the basis of the disease. Blood. 2022 Mar 3;139(9):1413-1418. [Content Brief]
[12]. A Toure, et al. Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling. J Biol Chem. 2001 Jun 8;276(23):20309-15. [Content Brief]
[13]. Mark E Burkard, et al. Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells. PLoS Biol. 2009 May 5;7(5):e1000111. [Content Brief]
[14]. A Touré, et al. MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells. J Biol Chem. 1998 Mar 13;273(11):6019-23. [Content Brief]