RAD51-associated protein 1
Definition:
References:
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[1]. Ann C Parplys, et al. RAD51AP1-deficiency in vertebrate cells impairs DNA replication. DNA Repair (Amst). 2014 Dec;24:87-97. [Content Brief]
[2]. Eloïse Dray, et al. Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Nat Struct Mol Biol. 2010 Oct;17(10):1255-9. [Content Brief]
[3]. Fengshan Liang, et al. Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex. Cell Rep. 2016 Jun 7;15(10):2118-2126. [Content Brief]
[4]. Jonathan Barroso-González, et al. RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres. Mol Cell. 2019 Oct 3;76(1):11-26.e7. [Content Brief]
[5]. Scott Cukras, et al. The USP1-UAF1 complex interacts with RAD51AP1 to promote homologous recombination repair. Cell Cycle. 2016 Oct;15(19):2636-2646. [Content Brief]
[6]. O V Kovalenko, et al. A novel nucleic acid-binding protein that interacts with human rad51 recombinase. Nucleic Acids Res. 1997 Dec 15;25(24):4946-53. [Content Brief]
[7]. Myun Hwa Dunlop, et al. Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair. J Biol Chem. 2012 Apr 6;287(15):12343-7. [Content Brief]
[8]. Claudia Wiese, et al. Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement. Mol Cell. 2007 Nov 9;28(3):482-90. [Content Brief]
[9]. Ann C Parplys, et al. NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability. Nucleic Acids Res. 2015 Nov 16;43(20):9817-34. [Content Brief]
[10]. Fengshan Liang, et al. DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response. Nat Commun. 2019 Jun 28;10(1):2849. [Content Brief]
[11]. Eloïse Dray, et al. Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1). Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3560-5. [Content Brief]
[12]. Mauro Modesti, et al. RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination. Mol Cell. 2007 Nov 9;28(3):468-81. [Content Brief]
[13]. Fengshan Liang, et al. The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair. J Biol Chem. 2020 Jun 12;295(24):8186-8194. [Content Brief]