2. Biology Dictionary
  3. Rho guanine nucleotide exchange factor 16

Rho guanine nucleotide exchange factor 16

Definition:

Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.

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