1. Biology Dictionary
  2. SH3 domain-binding protein 5

SH3 domain-binding protein 5

Definition:

Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25. Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.

Biomedical Dictionary

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