SHC-transforming protein 4

Definition:

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.

References:

[1]. Ernesta Fagiani, et al. RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas. Cancer Res. 2007 Apr 1;67(7):3064-73. [Content Brief]

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