Short transmembrane mitochondrial protein 1

Definition:

Microprotein involved in mitochondrial respiratory chain complex III (ubiquinol-cytochrome c oxidoreductase) and complex IV (mitochondrial cytochrome c oxidase complex) assembly. Required for the formation of mitochondrial supercomplexes (SCs). Also required for the activation of the NLRP3 inflammasome (By similarity).

References:

[1]. Ye Sang, et al. Mitochondrial micropeptide STMP1 promotes G1/S transition by enhancing mitochondrial complex IV activity. Mol Ther. 2022 Aug 3;30(8):2844-2855. [Content Brief]

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