Snurportin-1

Definition:

Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.

References:

[1]. Jason K Ospina, et al. Cross-talk between snurportin1 subdomains. Mol Biol Cell. 2005 Oct;16(10):4660-71. [Content Brief]

[2]. E Paraskeva, et al. CRM1-mediated recycling of snurportin 1 to the cytoplasm. J Cell Biol. 1999 Apr 19;145(2):255-64. [Content Brief]

[3]. J Huber, et al. Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure. EMBO J. 1998 Jul 15;17(14):4114-26. [Content Brief]

[4]. Anja Strasser, et al. Structural basis for m3G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1. EMBO J. 2005 Jul 6;24(13):2235-43. [Content Brief]

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