Sodium channel protein type 8 subunit alpha

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.; [Isoform 5]: In macrophages and melanoma cells, may participate in the control of podosome and invadopodia formation.