Sterol O-acyltransferase 2

Definition:

Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) and linolenoyl-CoA ((9Z,12Z,15Z)-octadecatrienoyl-CoA) as substrates. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.; [Isoform 2]: Has lower enzymatic activity compared to isoform 1.; [Isoform 3]: Has lower enzymatic activity compared to isoform 1.

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