Telomerase-binding protein EST1A
Definition:
References:
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[1]. Bryan E Snow, et al. Functional conservation of the telomerase protein Est1p in humans. Curr Biol. 2003 Apr 15;13(8):698-704. [Content Brief]
[2]. Andrea B Eberle, et al. SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells. Nat Struct Mol Biol. 2009 Jan;16(1):49-55. [Content Brief]
[3]. Eric Huntzinger, et al. SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. RNA. 2008 Dec;14(12):2609-17. [Content Brief]
[4]. Filip Glavan, et al. Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. EMBO J. 2006 Nov 1;25(21):5117-25. [Content Brief]
[5]. Andrew S Venteicher, et al. A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Science. 2009 Jan 30;323(5914):644-8. [Content Brief]
[6]. Patrick Reichenbach, et al. A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed. Curr Biol. 2003 Apr 1;13(7):568-74. [Content Brief]
[7]. Isao Kashima, et al. SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes Dev. 2010 Nov 1;24(21):2440-50. [Content Brief]
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