UBX domain-containing protein 4
Definition:
Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.
References:
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[1]. Precious J Lim, et al. Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. J Cell Biol. 2009 Oct 19;187(2):201-17. [Content Brief]
[2]. Jing Liang, et al. Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation. J Cell Sci. 2006 Oct 1;119(Pt 19):4011-24. [Content Brief]
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