Uridylate-specific endoribonuclease

Definition:

Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites.

References:

[1]. Pietro Laneve, et al. The tumor marker human placental protein 11 is an endoribonuclease. J Biol Chem. 2008 Dec 12;283(50):34712-9. [Content Brief]

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