Zinc finger protein 131

Definition:

Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.

References:

[1]. Xiao Han, et al. High-throughput cell-based screening reveals a role for ZNF131 as a repressor of ERalpha signaling. BMC Genomics. 2008 Oct 11;9:476. [Content Brief]

[2]. Yohan Oh, et al. Small ubiquitin-like modifier (SUMO) modification of zinc finger protein 131 potentiates its negative effect on estrogen signaling. J Biol Chem. 2012 May 18;287(21):17517-17529. [Content Brief]

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