country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187402A

Copy Link Print Information

DOPE-PEG2000-CSTSMLKAC

DOPE-PEG2000-CSTSMLKAC is an amphiphilic lipid-PEG-peptide conjugate composed of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the CSTSMLKAC peptide, a cyclic tumor-homing peptide with a disulfide bond formed by flanking cysteine residues. DOPE-PEG2000-CSTSMLKAC is used for tumor-targeted drug delivery through liposome and nanoparticle surface modification.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DOPE-PEG2000-CSTSMLKAC Chemical Structure

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

DOPE-PEG2000-CSTSMLKAC: surface functionalization of liposomes and lipid nanoparticles for tumor-targeted drug delivery and tumor imaging.
Structural composition:
(1) DOPE; a phospholipid with two unsaturated oleoyl chains that anchors into lipid bilayers and provides fusogenic activity for endosomal escape;
(2) PEG2000; a hydrophilic polymer that creates a steric barrier reducing opsonization and RES clearance, prolonging circulation time;
(3) CSTSMLKAC peptide; a cyclic tumor-homing peptide (cyclized via disulfide bond between terminal cysteines) that specifically binds to tumor vasculature or tumor cells, with the cyclic conformation enhancing structural stability, protease resistance, and binding affinity compared to linear peptides, directing nanocarriers to tumor sites for improved drug deposition.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

SMILES

[DOPE-PEG2000-CSTSMLKAC]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.