Zdhhc17 - zinc finger, DHHC domain containing 17 Gene

Also Known as Hip14; DHHC-17; A230053P19Rik; D130071N24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320150

Summary

Enables palmitoyltransferase activity and signaling receptor binding activity. Involved in axonogenesis; peptidyl-L-cysteine S-palmitoylation; and regulation of signal transduction. Acts upstream of or within protein palmitoylation. Located in Golgi apparatus. Is expressed in several structures, including early conceptus; heart; and oocyte. Used to study Huntington's disease. Orthologous to human ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17). [provided by Alliance of Genome Resources, Apr 2022]

Zdhhc17 Products (3)

mRNA Protein Name
NM_001359622.1 NP_001346551.1 palmitoyltransferase ZDHHC17 isoform 2
NM_001359624.1 NP_001346553.1 palmitoyltransferase ZDHHC17 isoform 3
NM_172554.2 NP_766142.2 palmitoyltransferase ZDHHC17 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables palmitoyltransferase activity IDA
IDA: Inferred from direct assay
15603741 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
25253725 MGI
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
26232532 MGI
Biological Process GO Annotation Evidence References Source
involved in axonogenesis IMP
IMP: Inferred from mutant phenotype
26232532 MGI
involved in peptidyl-L-cysteine S-palmitoylation IDA
IDA: Inferred from direct assay
28167757 MGI
acts upstream of or within protein palmitoylation IDA
IDA: Inferred from direct assay
15603741 MGI
involved in protein palmitoylation IDA
IDA: Inferred from direct assay
18596047 MGI
involved in regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
26232532 MGI
involved in regulation of modification of synapse structure, modulating synaptic transmission IDA
IDA: Inferred from direct assay
24277827 MGI
involved in regulation of modification of synapse structure, modulating synaptic transmission IMP
IMP: Inferred from mutant phenotype
24277827 MGI
involved in regulation of neurotrophin TRK receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
26232532 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
18596047 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
24277827 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
24277827 MGI
is active in perforant pathway to dendrate granule cell synapse IDA
IDA: Inferred from direct assay
24277827 MGI
is active in perforant pathway to dendrate granule cell synapse IMP
IMP: Inferred from mutant phenotype
24277827 MGI
is active in postsynaptic Golgi apparatus IDA
IDA: Inferred from direct assay
15603740 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

palmitoyltransferase ZDHHC17

  • DHHC domain-containing cysteine-rich protein 17

  • acyltransferase ZDHHC17

  • acyltransferase ZDHHC7

  • huntingtin interacting protein 14

  • zinc finger DHHC domain-containing protein 17

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16016 ZDHHC17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zdhhc17 NCBI NCBI:23390