ZDHHC17 - zinc finger DHHC-type palmitoyltransferase 17 Gene

Homo sapiens

Also known as HIP3; HYPH; HIP14; DHHC17; DHHC-17; HSPC294

Gene ID: 23390 | Gene type: protein coding

About ZDHHC17

Cytogenetic location: 12q21.2 Genomic coordinates (GRCh38): 12:76,764,115-76,853,701 (from NCBI)

This gene has 16 transcripts (splice variants), 212 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 20.0), endometrium (RPKM 12.2) and 25 other tissues.

Summary

Enables identical protein binding activity and protein-cysteine S-palmitoyltransferase activity. Involved in lipoprotein transport and protein palmitoylation. Located in Golgi membrane; Golgi-associated vesicle membrane; and aggresome. [provided by Alliance of Genome Resources, Apr 2022]

ZDHHC17 Products(2)

mRNA	Protein	Name
NM_001359626.1	NP_001346555.1	palmitoyltransferase ZDHHC17 isoform 2
NM_015336.4	NP_056151.2	palmitoyltransferase ZDHHC17 isoform 1

ZDHHC17 Protein Structure

Ank_2

Ank

DHHC

0
100
200
300
400
500
632 a.a.

Protein Preferred Names

Protein Names

palmitoyltransferase ZDHHC17

DHHC domain-containing cysteine-rich protein 17

Related Diseases

Diseases

Alias

Huntington Disease

Huntington'S Disease	Huntington Chorea
Huntington'S Chorea	HD
Huntington Chronic Progressive Hereditary Chorea	Juvenile Huntington Disease
Chronic Progressive Chorea	Chronic Progressive Hereditary Chorea
Hc - [Huntington Chorea]	Hereditary Chorea
Progressive Hereditary Chorea

Type 1 Diabetes Mellitus 2

Diabetes Mellitus, Noninsulin-Dependent, 1	Diabetes Mellitus, Insulin-Dependent, 2
IDDM2	Insulin-Dependent Diabetes Mellitus 2
NIDDM1	Diabetes Mellitus, Noninsulin-Dependent 1
T1D2	Type 2 Diabetes Mellitus 1
T2D1	Noninsulin-Dependent Diabetes Mellitus 1
Diabetes Mellitus, Non-Insulin-Dependent, 1	Type 2 Diabetes Mellitus 1, Susceptibility To
Diabetes Mellitus, Insulin-Dependent, Type 2	Diabetes Mellitus, Non-Insulin-Dependent

Neuronal Ceroid Lipofuscinosis

Hereditary Ceroid Lipofuscinosis	Batten Disease
Ncl	Neuronal Ceroid-Lipofuscinoses
Lipofuscinosis, Ceroid, Neuronal	Juvenile Neuronal Ceroid Lipofuscinosis
Cerebromacular Dystrophy	Cerebromacular Degeneration
Ceroid-Lipofuscinosis	Ncl - [Neuronal Ceroid Lipofuscinosis]
Amaurotic Familial Idiocy	Amaurotic Idiocy
Amaurotic Idiot	Neuronal Lipofuscinosis
Pigmentary Retinal Lipoid Neuronal Heredodegeneration

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16016	ZDHHC17 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZDHHC17	RGD	RGD:1595790
Felis catus	ZDHHC17	VGNC	VGNC:67206
Macaca mulatta	ZDHHC17	VGNC	VGNC:79137
Bos taurus	ZDHHC17	VGNC	VGNC:37132
Mus musculus	ZDHHC17	MGD	MGI:2445110
Canis familiaris	ZDHHC17	VGNC	VGNC:48583

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